《CRYPTOCOCCAL INFECTIONS IN PATIENTS WITH AIDS》內(nèi)容預(yù)覽
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《CRYPTOCOCCAL INFECTIONS IN PATIENTS WITH AIDS》內(nèi)容簡介

    CRYPTOCOCCALINFECTIONSINPATIENTSWITHAIDS
    StephenJ.Gluckman,M.D.
    Botswana-UPENNPartnership
    Microbiology
    lEncapsulatedyeast
    l4serotypes
    lA(C.neoformansvgrubii)
    lBandC(C.gatti)
    lD(C.neoformansvneoformans)
    lAlltypescancausehumandisease
    lLifecycle
    lAsexual:yeastthatreproducebybudding
    lHumaninfections
    lSexual:onlyseeninthelaboratory
    EcologyandEpidemiology
    lWorldwide
    lC.neoformansassociatedwithbirddroppings
    lC.gattinotassociatedwithbirds,associatedwitheucalyptustrees
    lGenerallyaninfectionofimmunocompromisedbutcancauseclinicaldiseaseinhealthypersons
    lDecreasedCell-mediatedimmunity
    lAIDS–CD4usually<100
    lProlongedcorticosteroids
    lOrgantransplant
    EcologyandEpidemiology
    l15-30%ofAIDSpatientsinSub-SaharanAfrica*
    lMuchlesscommoninchildren
    lNopersontopersontransmission
    *Powderly,WGClinInfectDis1993

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